Pascal Reynier Selected Research

Carnitine (L-Carnitine)

6/2022	Metabolomic Profiling of Angiotensin-II-Induced Abdominal Aortic Aneurysm in Ldlr-/- Mice Points to Alteration of Nitric Oxide, Lipid, and Energy Metabolisms.
11/2016	The metabolomic signature of Leber's hereditary optic neuropathy reveals endoplasmic reticulum stress.

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Pascal Reynier Research Topics

Disease

15	Mitochondrial Diseases (Mitochondrial Disease) 12/2021 - 09/2002
13	Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy) 01/2023 - 09/2002
12	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 06/2020 - 06/2003
10	Optic Nerve Diseases (Optic Neuropathy) 01/2021 - 02/2008
9	Neoplasms (Cancer) 01/2022 - 10/2003
4	MELAS Syndrome (Syndrome, MELAS) 07/2022 - 06/2012
4	Insulin Resistance 06/2022 - 01/2018
4	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 06/2022 - 01/2017
4	Optic Atrophy 01/2022 - 02/2008
4	Hypertension (High Blood Pressure) 01/2022 - 01/2020
4	Hypothermia 01/2021 - 10/2018
4	Deafness (Deaf Mutism) 10/2009 - 11/2007
3	Inflammation (Inflammations) 09/2023 - 01/2018
3	Stroke (Strokes) 07/2023 - 01/2017
3	Open-Angle Glaucoma (Glaucoma, Open Angle) 01/2020 - 07/2015
3	Nervous System Diseases (Neurological Disorders) 10/2019 - 09/2002
3	Glaucoma 01/2019 - 01/2018
3	Muscular Diseases (Myopathy) 01/2019 - 02/2007
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2017 - 10/2010
3	Inherited Peripheral Neuropathy 12/2016 - 02/2010
2	Breast Neoplasms (Breast Cancer) 12/2023 - 11/2021
2	Lactic Acidosis 07/2022 - 12/2021
2	Dry Eye Syndromes (Dry Eye Syndrome) 01/2022 - 10/2021
2	Intellectual Disability (Idiocy) 01/2022 - 01/2018
2	Tuberculosis (Tuberculoses) 05/2021 - 03/2010
2	Macular Degeneration (Age-Related Maculopathy) 02/2020 - 01/2018
2	Type 2K Charcot-Marie-Tooth disease 01/2020 - 04/2009
2	Ganglion Cysts (Ganglion) 03/2019 - 10/2017
2	Parkinson Disease (Parkinson's Disease) 01/2018 - 03/2013
2	Alzheimer Disease (Alzheimer's Disease) 01/2018 - 01/2017
2	Drug Resistant Epilepsy 01/2018 - 01/2017
2	Hemolysis 12/2016 - 01/2016
2	Acute Intermittent Porphyria (Porphyria, Acute) 09/2015 - 06/2014
2	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 12/2011 - 04/2009
2	Carcinogenesis 06/2011 - 03/2004
2	Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia) 02/2008 - 02/2008
2	Ataxia (Dyssynergia) 02/2008 - 02/2008
2	Papillary Carcinoma 06/2005 - 03/2004
2	Oxyphilic Adenoma (Oncocytoma) 04/2005 - 10/2003
1	Myocardial Ischemia (Ischemic Heart Diseases) 09/2023
1	Infarction (Infarctions) 09/2023
1	Reperfusion Injury 09/2023
1	Iron Deficiencies 09/2023

Drug/Important Bio-Agent (IBA)

29	Mitochondrial DNA (mtDNA)IBA 01/2023 - 09/2002
15	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2004
12	Biomarkers (Surrogate Marker)IBA 09/2023 - 01/2018
8	Dynamins (Dynamin)IBA 10/2019 - 06/2003
7	GTP Phosphohydrolases (GTPases)IBA 10/2019 - 06/2003
6	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 06/2005
5	Amino Acids FDA Link 07/2023 - 11/2016
5	Mitochondrial Proteins (Mitochondrial Protein)IBA 05/2020 - 12/2004
4	Arginine (L-Arginine)FDA Link 01/2023 - 06/2012
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2022 - 06/2012
4	SpermineIBA 01/2022 - 01/2018
4	Lactic Acid (Lactate)FDA LinkGeneric 01/2022 - 01/2017
4	EnzymesIBA 01/2016 - 03/2013
3	Ketone BodiesIBA 07/2022 - 01/2017
3	Fatty Acids (Saturated Fatty Acids)IBA 06/2022 - 09/2014
3	Taurine FDA Link 06/2022 - 01/2019
3	Oxygen (Dioxygen)IBA 01/2022 - 01/2021
3	Phosphatidylcholines (Phosphatidylcholine)IBA 01/2021 - 11/2016
3	Retinaldehyde (Retinal)IBA 03/2019 - 01/2013
2	Nitric Oxide Synthase (NO Synthase)IBA 07/2023 - 01/2021
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 07/2023 - 06/2022
2	ArginaseIBA 07/2023 - 05/2019
2	Adenosine Triphosphate (ATP)IBA 01/2023 - 08/2009
2	LipidsIBA 06/2022 - 01/2018
2	Carnitine (L-Carnitine)FDA LinkGeneric 06/2022 - 11/2016
2	Thyrotropin Receptors (Thyrotropin Receptor)IBA 01/2022 - 03/2004
2	Pyruvic Acid (Pyruvate)IBA 01/2022 - 09/2012
2	Tryptophan (L-Tryptophan)FDA Link 01/2021 - 05/2019
2	Niacinamide (Nicotinamide)FDA LinkGeneric 01/2021 - 01/2019
2	SphingomyelinsIBA 01/2021 - 11/2016
2	CytokinesIBA 05/2020 - 01/2018
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 01/2009
2	ResveratrolIBA 01/2020 - 01/2015
2	Glucose (Dextrose)FDA LinkGeneric 05/2018 - 09/2012
2	SpermidineIBA 01/2018 - 11/2016
2	PolyaminesIBA 01/2018 - 01/2018
2	Protein Isoforms (Isoforms)IBA 01/2018 - 06/2011
2	Hormones (Hormone)IBA 04/2017 - 03/2004
2	Heme (Haem)IBA 09/2015 - 06/2014
2	Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)IBA 09/2015 - 06/2014
2	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 02/2008 - 02/2008
1	Vitamin D FDA LinkGeneric 12/2023
1	hydroxide ionIBA 12/2023
1	25-hydroxyvitamin DIBA 12/2023
1	1,25-dihydroxyvitamin DIBA 12/2023
1	Evans Blue (Blue, Evans)FDA Link 09/2023
1	Kynurenic Acid (Kynurenate)IBA 09/2023
1	C-Reactive ProteinIBA 09/2023
1	Ferritins (Ferritin)IBA 09/2023
1	Serine (L-Serine)FDA Link 07/2023
1	salicylhydroxamic acid (SHAM)IBA 07/2023
1	CollagenIBA 07/2023
1	Lysine (L-Lysine)FDA Link 07/2023
1	AsparagineIBA 07/2023
1	Adenylyl Cyclases (Adenylyl Cyclase)IBA 01/2023

Therapy/Procedure

7	Therapeutics 10/2021 - 06/2012
3	Ketogenic Diet 07/2022 - 01/2017